????? ??? ???? ??? ?? ????! ???? ????? ???????? ?????? ?????? ????? ???? ?? ??????????? ??? ?? ???? ????? ??? ???? ??????? ????? ??????????? ???? ????? ?? ???? ??????? ???????? ??????? ??? ???? ??????? ?? ?????? ???? ??????? ??? ?? ?? ???? ?? ????? ??????.On average, age larger than 65 yrs was connected with a rise in oxymorphone AUC and Cmax. Init